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Published research on the effectiveness of chlorella in binding toxic chemicals, metals, moulds (mycotoxins) and radioactive elements.
Chlorella’s ability to bind toxic chemicals.
Dioxins
Nakano, S., Takekoshi, H., Nakano, M. 2007. Chlorella (Chlorella pyrenoidosa) supplementation decreases dioxin and increases immunoglobulin A concentrations in breast milk. J Med Food; 10(1): 134-42. PMID 17472477.http://www.ncbi.nlm.nih.gov/pubmed/17472477
Nakano, W., Noguchi, T., Takekoshi, H., Suzuki, G., Nakano, M. 2005. Maternal-fetal distribution and transfer of dioxins in pregnant women in Japan, and attempts to reduce maternal transfer with chlorella(Chlorella pyrenidosa) supplements. Chemosphere; 61(9):1244-55. PMID15985279. http://www.ncbi.nlm.nih.gov/pubmed/15985279
Bisphenol A.
Hirooka, T., Nagase, H., Uchida, K., Hiroshige, Y., Ehara, Y., Nishihara, T., Miyamoto, K., Hirata, Z. 2005. Biodegredation of bisphenol A and disappearance of its estrogenic activity by the green algae Chlorella fusca var. vacuolata. Environ Toxicol Chem; 24(8): 1896-901. PMID 16152959. http://www.ncbi.nlm.nih.gov/pubmed/16152959
Zhang, W., Xiong, B., Sun, W.F., An, S., Lin, K.F., Guo, M.J., Cui, X.H. 2014. Acute and chronic toxic effects of bisphenol A on Chlorella pyrenoidosa and Scenedesmus obliquus. Environ Toxicol; 29 (6): 714-22. PMID 22887798. http://www.ncbi.nlm.nih.gov/pubmed/22887798
Heterocyclic amines
Lee, I., Tran, M., Evans-Nguyen, T., Stickle, D., Kim, S., Han, J., Park, J.Y., Yang, M. 2015. Detoxification of chlorella supplement on heterocyclic amines in Korean young adults. Environ Toxicol Pharmacol; 39(1): 441-6. PMID 25590673 http://www.ncbi.nlm.nih.gov/pubmed/25590673
Lee, Y.J., Hong, H.J., Kim, J.Y., Lee, K.W., Kwon, O. 2013. Dietry Chlorella protects against heterocyclic amine-induced aberrant gene expression in the rat colon by increasing fecal excretion of unmetabolised PhIP. Food Chem Toxicol; 56: 272-7. http://www.ncbi.nlm.nih.gov/pubmed/23466459
Advanced glycation end products (AGE) (metabolic toxins)
Yamagishi, S., Nakamura, K., Inoue, H. 2005. Therapeutic potentials of unicellular green alga Chlorella in advanced glycation end product (AGE)-related disorders. Med Hypotheses; 65(5):953-5.http://www.ncbi.nlm.nih.gov/pubmed/15996828
The ability of Chlorella to bind toxic metals.
Caesium
Avery, S.V., Codd, G.A., Gadd, G.M. 1991. Replacement of cellular potassium by caesium in Chlorella emersonii: differential sensitivity of photoautotrophic and chemoheterotrophic growth. Journal of general microbiology; 138, 69-76.
Platinum, Rhodium, Lead
Shams, L., Turner, A., Millward, G.E., Brown, M.T. 2014. Extra- and intra-cellular accumulation of platinum group elements by the marine microalga, Chlorella stigmatophora. Water Res, 1; 50: 432-40. http://www.ncbi.nlm.nih.gov/pubmed/24268058
Copper, Chromium, Lead, Cadmium.
Kumar, R.M., Frankilin, J., Raj, S.P. 2013. Accumulation of heavy metals (Cu,Cr,Pb and Cd) in freshwater micro algae (Chlorella sp.) J Environ Sci Eng; 55(3): 371-6http://www.ncbi.nlm.nih.gov/pubmed/25509955
Cadmium
Shim, J.Y., Shin, S.H., Han, J.G., Park, H.S., Lim, B.L., Chung, K.W., Om, A.S. 2008. Protective effects of Chlorella vulgaris on liver toxicity in cadmium administered rats. J Med Food; 11(3): 479-85. http://www.ncbi.nlm.nih.gov/pubmed/18800895
Mercury
Uchikawa, T., Maruyama, I., Kumamoto, S., Ando, Y., Yasutake, A. 2011. Chlorella supresses methylmercury transfer to the fetus in pregnant mice. J Toxicol Sci; 36(5): 675-680. http://www.ncbi.nlm.nih.gov/pubmed/22008543
Uchikawa T, Yasutake A, Kumamoto Y, Maruyama I, Kumamoto S, Ando Y. 2010. The influence of Parachlorella beyerinckii CK-5 on the absorption and excretion of methylmercury (MeHg) in mice.
Uchikawa T, Kumamoto Y, Maruyama I, Kumamoto S, Ando Y, Yasutake A. The enhanced elimination of tissue methylmercury in Parachlorella beijerinckii-fed mice. Journal of Toxicological Sciences. 2011;36(1):121–126. https://www.ncbi.nlm.nih.gov/pubmed/21297350
J Toxicol Sci. 2010 ;35(1):101-5.
https://www.ncbi.nlm.nih.gov/pubmed/20118630
Nickel
Akhtar, N., Iqbal, J., Iqbal, M. 2004. Removal and recovery of nikel (II) from aqueous solution by loofa sponge-immobilised biomass of chlorella sorokiniana: characterisation studies. J Hazard Mater; 108(1-2): 85-94. http://www.ncbi.nlm.nih.gov/pubmed/15081166
Arsenic
Zahran, E., Risha, E. 2014. Modulatory role od dietry Chlorella vulgaris powder against arsenic-induced immunotoxicity and oxidative stress in Nile tilapia (Oreochromis niloticus). Fish Shellfish Immunol; 41(2): 654-62. http://www.ncbi.nlm.nih.gov/pubmed/25304544
Moulds
Hope, J., 2013. A review of the mechanism of injury and treatment approaches for illness resulting from exposure to water-damaged buildings, mold and mycotoxins. Scientific World Journal; 767482.
http://www.ncbi.nlm.nih.gov/pubmed/23710148
Radioactive elements
UVB
http://www.ncbi.nlm.nih.gov/pubmed/18474460
Gamma rays
http://www.ncbi.nlm.nih.gov/pubmed/8543329
http://www.ncbi.nlm.nih.gov/pubmed/8176669
http://www.ncbi.nlm.nih.gov/pubmed/2688154
Cobalt
Avio, C.M., Campagni, A. 1976. (Absorption of radiocobalt in Chlorella vulgaris)?1Assorbimentodi radicobalto in “Chlorella vulgaris”. G Batteriol Virol Immunol; 67(7-12):188-202. http://www.ncbi.nlm.nih.gov/pubmed/1028642
Uranium
Horikoshi, T., Nakajima, A., Sakaguchi, T. 1979. Uptake of uranium by various cell fractions of Chlorella regularis. Radioisotopes; 28(8): 485-8. http://www.ncbi.nlm.nih.gov/pubmed/542634